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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPS8L2
All Species:
13.33
Human Site:
Y415
Identified Species:
41.9
UniProt:
Q9H6S3
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9H6S3
NP_073609.2
715
80621
Y415
R
E
P
Q
V
P
L
Y
V
P
K
F
H
S
G
Chimpanzee
Pan troglodytes
XP_512904
745
82543
R452
P
E
E
G
P
P
Y
R
P
E
F
F
S
G
W
Rhesus Macaque
Macaca mulatta
XP_001116697
615
68955
K350
E
F
V
D
C
F
Q
K
I
K
L
A
I
N
L
Dog
Lupus familis
XP_534881
791
88639
Y399
K
E
Q
F
I
A
P
Y
V
P
R
F
R
N
G
Cat
Felis silvestris
Mouse
Mus musculus
Q99K30
729
82211
Y418
R
E
P
Q
V
P
L
Y
V
P
K
F
R
S
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510664
556
62861
Q291
G
M
L
S
P
N
M
Q
Q
P
S
S
I
D
L
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002666818
677
76506
Y403
K
D
Q
C
A
P
L
Y
V
P
K
F
R
N
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785396
970
107261
Y569
K
D
R
P
V
S
R
Y
V
P
R
F
R
D
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
42.2
79.7
42.5
N.A.
84
N.A.
N.A.
29
N.A.
N.A.
56.5
N.A.
N.A.
N.A.
N.A.
24.6
Protein Similarity:
100
58.2
80.8
60.1
N.A.
90.1
N.A.
N.A.
46.1
N.A.
N.A.
70.7
N.A.
N.A.
N.A.
N.A.
40.5
P-Site Identity:
100
20
0
40
N.A.
93.3
N.A.
N.A.
6.6
N.A.
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
40
P-Site Similarity:
100
20
13.3
66.6
N.A.
93.3
N.A.
N.A.
13.3
N.A.
N.A.
73.3
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
13
13
0
0
0
0
0
13
0
0
0
% A
% Cys:
0
0
0
13
13
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
25
0
13
0
0
0
0
0
0
0
0
0
25
0
% D
% Glu:
13
50
13
0
0
0
0
0
0
13
0
0
0
0
0
% E
% Phe:
0
13
0
13
0
13
0
0
0
0
13
75
0
0
0
% F
% Gly:
13
0
0
13
0
0
0
0
0
0
0
0
0
13
63
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% H
% Ile:
0
0
0
0
13
0
0
0
13
0
0
0
25
0
0
% I
% Lys:
38
0
0
0
0
0
0
13
0
13
38
0
0
0
0
% K
% Leu:
0
0
13
0
0
0
38
0
0
0
13
0
0
0
25
% L
% Met:
0
13
0
0
0
0
13
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
13
0
0
0
0
0
0
0
38
0
% N
% Pro:
13
0
25
13
25
50
13
0
13
75
0
0
0
0
0
% P
% Gln:
0
0
25
25
0
0
13
13
13
0
0
0
0
0
0
% Q
% Arg:
25
0
13
0
0
0
13
13
0
0
25
0
50
0
0
% R
% Ser:
0
0
0
13
0
13
0
0
0
0
13
13
13
25
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
13
0
38
0
0
0
63
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
13
% W
% Tyr:
0
0
0
0
0
0
13
63
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _